Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837947 | 0.84 | TRPM8 (0.52) | TRPM8ALDH1A1MAPTPOLB | |
| SCHEMBL6778618 | 0.84 | PPARA (0.50) | RIPK1POLB | |
| SCHEMBL6775901 | 0.82 | PPARA (0.68) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL6785304 | 0.81 | PPARA (0.44) | MAPTRIPK1POLB | |
| SCHEMBL4888008 | 0.81 | PPARA (0.48) | MAPTPOLB | |
| SCHEMBL7218857 | 0.80 | PPARA (0.47) | ALDH1A1MAPTPOLB | |
| SCHEMBL1645027 | 0.79 | ALDH1A1 (0.54) | TRPM8ALDH1A1MAPTTSHRHTT | |
| SCHEMBL5224390 | 0.79 | PPARA (0.42) | MAPTPOLB | |
| SCHEMBL11884379 | 0.78 | THRA (0.53) | TRPM8ALDH1A1MAPTRIPK1ALOX5 | |
| SCHEMBL64663 | 0.76 | ALDH1A1 (0.51) | TRPM8ALDH1A1MAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |