Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.74 |
| ▸ | RXRA | P19793 | 2/20 | 0.70 |
| ▸ | RXRB | P28702 | 2/20 | 0.70 |
| ▸ | CTRC | Q99895 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | ALAD | P13716 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.50 |
| ▸ | CDH1 | P12830 | 1/20 | 0.50 |
| ▸ | APC | P25054 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491622 | 0.87 | RXRA (0.64) | TPMTRXRARXRBCTRCALOX15 | |
| SCHEMBL23699 | 0.86 | TPMT (1.00) | TPMTRXRARXRBALOX15TSHR | |
| SCHEMBL28214359 | 0.86 | TPMT (1.00) | TPMTRXRARXRBALOX15TSHR | |
| SCHEMBL2041424 | 0.84 | TSHR (0.85) | RXRARXRBCTRCALOX15TSHR | |
| Iodide SCHEMBL27041428 | 0.84 | TPMT (0.94) | TPMTRXRARXRBALOX15TSHR | |
| Hydrochloric Acid SCHEMBL10387707 | 0.84 | TPMT (0.94) | TPMTRXRARXRBALOX15TSHR | |
| SCHEMBL8023966 | 0.84 | TPMT (0.94) | TPMTRXRARXRBALOX15TSHR | |
| Bromide SCHEMBL27041421 | 0.84 | TPMT (0.94) | TPMTRXRARXRBALOX15TSHR | |
| SCHEMBL412461 | 0.83 | RXRA (1.00) | TPMTRXRARXRBALOX15TSHR | |
| Hydrochloric Acid SCHEMBL4268387 | 0.82 | TSHR (0.81) | RXRARXRBCTRCALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824767-A | MOLDING MATERIALS FOR MELT SPINNING AND EXTRUSION CONTAINING A BARIUM COMPOUND AND A LUBRICANT; REDUCED ADHESION TO METAL SURFACES | HOECHST CELANESE CORPORATION (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0818493-A2 | Poly(arylene sulfide) composition having good processability | HOECHST CELANESE CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5652287-A | BLEND WITH CURED SILICONE RUBBER | HOECHST CELANESE CORPORATION (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0372829-B1 | Poly(arylene sulfide) sheet and production process thereof | KUREHA CHEMICAL IND CO LTD (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5013823-A | Excellent in planarity and smoothness | KUREHA KAGAKU KOGYO K.K. (JP) | 1991-05-07 | — | — | US | disclosed |