Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684444 | 0.83 | L3MBTL1 (0.57) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL571114 | 0.79 | TDP1 (0.58) | KMT2AMAPTMAPK1MEN1TDP1 | |
| Benzene SCHEMBL28690163 | 0.79 | MAPK1 (0.58) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL7085528 | 0.79 | MAPK1 (0.58) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL28587168 | 0.78 | L3MBTL1 (0.49) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL29092014 | 0.77 | KMT2A (0.56) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL22313390 | 0.77 | CES1 (0.56) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL136826 | 0.77 | CES1 (0.56) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL4621332 | 0.77 | MAPT (0.56) | KMT2AMAPTMAPK1MEN1TDP1 | |
| SCHEMBL6752860 | 0.76 | CES1 (0.54) | KMT2AMAPTMAPK1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | claimed |
| EP-0000745-B1 | SALT OF AN OPTICALLY ACTIVE ISOMER OF PHENYLGLYCINE AND AN OPTICALLY ACTIVE ISOMER OF 2-AMINO BUTANOL AND PROCESS FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-15 | — | — | EP | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| EP-0000745-A1 | Salt of an optically active isomer of phenylglycine and an optically active isomer of 2-amino butanol and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-5776948-A | BACTERICIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5527900-A | VIRICIDES; ANTI-HTLV ACTIVITY | STITCHING REGA VZW (BE) | 1996-06-18 | — | — | US | disclosed |
| EP-0530407-B1 | Substituted, nucleoside derivatives, methods for their preparation and pharmaceutical compositions containing them | STICHTING REGA V Z W (BE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0664288-A1 | FLUOROQUINOLINE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-07-26 | — | — | EP | disclosed |
| EP-0530407-A1 | Substituted, nucleoside derivatives, methods for their preparation and pharmaceutical compositions containing them | Stichting REGA V.Z.W. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5144027-A | Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4931555-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-4036847-A | ANTIBACTERIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-07-19 | — | — | US | disclosed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |