Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632730 | 0.85 | ALOX5 (0.50) | ADRB1KDM4EALDH1A1HTTALOX5 | |
| SCHEMBL8633112 | 0.81 | AHR (0.42) | KDM4EALDH1A1HTTRECQLALOX5 | |
| SCHEMBL28683908 | 0.74 | DRD2 (0.53) | DRD2DRD3ADRB1P2RX7 | |
| SCHEMBL2470770 | 0.72 | RAD51 (0.48) | DRD2DRD3ADRB1P2RX7ALDH1A1 | |
| SCHEMBL10749011 | 0.71 | DBH (0.39) | KDM4EALDH1A1HTTRECQLDDB1 | |
| SCHEMBL1878252 | 0.71 | POLB (0.47) | DRD2P2RX7KDM4EALDH1A1HCAR1 | |
| SCHEMBL11097554 | 0.70 | MGLL (0.46) | KDM4EALDH1A1HTTDDB1CRBN | |
| SCHEMBL8631856 | 0.70 | KMT2A (0.66) | ALDH1A1HTTHCAR1DDB1CRBN | |
| SCHEMBL2536247 | 0.70 | DDB1 (0.72) | ADRB1P2RX7KDM4EALDH1A1ALOX5 | |
| SCHEMBL7555132 | 0.70 | DDB1 (0.45) | KDM4EALDH1A1HTTDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850226-A1 | NOVEL IMIDAZOLINE-2,4-DIONES WITH AN ORTHO-SUBSTITUTED AR(ALK)YL RADICAL IN POSITION 1, HAVING AN ANTI-CONVULSIVE EFFECT, AND PROCESS FOR THEIR PRODUCTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1998-07-01 | — | — | EP | claimed |
| WO-1997006149-A1 | NOVEL IMIDAZOLINE-2,4-DIONES WITH AN ORTHO-SUBSTITUTED AR(ALK)YL RADICAL IN POSITION 1, HAVING AN ANTI-CONVULSIVE EFFECT, AND PROCESS FOR THEIR PRODUCTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-02-20 | — | — | WO | claimed |
| CN-105777647-B | A kind of method for synthesizing 1- isopropylamino formamides -3- (3,5- dichlorophenyls) hydantoins | 江苏快达农化股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-105777647-B | A kind of method for synthesizing 1- isopropylamino formamides -3- (3,5- dichlorophenyls) hydantoins | 江苏快达农化股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-103874410-A | Composition, method for producing the composition, and phytosanitary formulation containing same | RHODIA OPERATIONS | 2014-06-18 | — | — | CN | disclosed |
| US-5817685-A | ANTIEPILEPTIC AGENT | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0850226-A1 | NOVEL IMIDAZOLINE-2,4-DIONES WITH AN ORTHO-SUBSTITUTED AR(ALK)YL RADICAL IN POSITION 1, HAVING AN ANTI-CONVULSIVE EFFECT, AND PROCESS FOR THEIR PRODUCTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997006149-A1 | NOVEL IMIDAZOLINE-2,4-DIONES WITH AN ORTHO-SUBSTITUTED AR(ALK)YL RADICAL IN POSITION 1, HAVING AN ANTI-CONVULSIVE EFFECT, AND PROCESS FOR THEIR PRODUCTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-02-20 | — | — | WO | disclosed |