Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628556 | 0.90 | GRM5 (0.47) | PPARGKCNH2GRM5MRGPRX4PDE10A | |
| SCHEMBL8694570 | 0.90 | GRM5 (0.43) | PPARGKCNH2GRM5MRGPRX4L3MBTL1 | |
| SCHEMBL8692569 | 0.90 | PPARG (0.42) | PPARGKCNH2GRM5MRGPRX4L3MBTL1 | |
| SCHEMBL8627523 | 0.88 | MAPT (0.45) | PPARGKCNH2GRM5MRGPRX4L3MBTL1 | |
| SCHEMBL8629313 | 0.88 | MAPT (0.45) | PPARGKCNH2GRM5MRGPRX4L3MBTL1 | |
| SCHEMBL8630455 | 0.87 | L3MBTL1 (0.37) | PPARGKCNH2GRM5L3MBTL1MAP4K4 | |
| SCHEMBL8627197 | 0.86 | RECQL (0.42) | PPARGGRM5L3MBTL1MAP4K4CYP1A2 | |
| SCHEMBL8721109 | 0.85 | F2 (0.44) | PPARGGRM5L3MBTL1MAP4K4CYP1A2 | |
| SCHEMBL8721952 | 0.79 | PTGER1 (0.44) | PPARGGRM5CYP2C19 | |
| SCHEMBL8785419 | 0.78 | KMT2A (0.41) | PPARGGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |