Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10815593 | 1.00 | ALDH1A1 (0.71) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Fumaric Acid SCHEMBL10776632 | 1.00 | ALDH1A1 (0.71) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| SCHEMBL1476972 | 0.92 | ALDH1A1 (0.60) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Maleic Acid SCHEMBL11159541 | 0.92 | ALDH1A1 (0.60) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Crotonic Acid SCHEMBL27942251 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Maleic Acid SCHEMBL28328814 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Hydrogen Peroxide SCHEMBL9143793 | 0.87 | — | — | |
| SCHEMBL7640509 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Acrylic Acid SCHEMBL7214354 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Acrylic Acid SCHEMBL215856 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HCAR2TSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113621110-B | Unclonable anti-counterfeiting material based on nanosphere self-assembly and preparation method and application thereof | 广东工业大学 | 2022-12-16 | — | — | CN | claimed |
| CN-113621110-A | Unclonable anti-counterfeiting material based on nanosphere self-assembly and preparation method and application thereof | 广东工业大学 | 2021-11-09 | — | — | CN | claimed |
| CN-109422846-A | Polymethyl methacrylate-maleic acid fatty alcohol ester sodium salt-argentum nano composite material and preparation method thereof | 天津大学 | 2019-03-05 | — | — | CN | claimed |
| CN-109422847-A | Polymethyl methacrylate-maleic acid fatty alcohol ester sodium salt-aluminum oxide nanocomposite and preparation method thereof | 天津大学 | 2019-03-05 | — | — | CN | claimed |
| CN-1306644-C | Composite polymer electrolyte for lithium secondary battery containing single ion conductor and method of manufacturing it | KOREA ELECTRONICS TELECOMM (KR) | 2007-03-21 | — | — | CN | claimed |
| CN-1610170-A | Composite polymer electrolyte for lithium secondary battery containing single ion conductor and method of manufacturing it | KOREA ELECTRONICS TELECOMM (KR) | 2005-04-27 | — | — | CN | claimed |
| CN-113621110-B | Unclonable anti-counterfeiting material based on nanosphere self-assembly and preparation method and application thereof | 广东工业大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-114516962-A | High-light-transmittance sensitive resin and color photosensitive resin composition using same | 北京鼎材科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-113621110-A | Unclonable anti-counterfeiting material based on nanosphere self-assembly and preparation method and application thereof | 广东工业大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-108739689-A | A kind of wear-resisting fishing net of copolymer reinforced nylon | 巢湖市俊业渔具有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105754134-B | A kind of preparation method of polyalcohol stephanoporate microballoons | 昆明理工大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-105001610-B | Composite and preparation method thereof | 北京化工大学 | 2016-10-05 | — | — | CN | disclosed |
| CN-103353707-B | Coating composition for photoresist | 罗门哈斯电子材料有限公司 | 2016-06-29 | — | — | CN | disclosed |
| EP-0251513-B1 | Acid modified adhesive compositions | ILLINOIS TOOL WORKS (US) | 1994-08-17 | — | — | EP | disclosed |
| US-4959405-A | ACRYLATE, STRONG ORGANIC ACID | ILLINOIS TOOL WORKS, INC. | 1990-09-25 | — | — | US | disclosed |
| EP-0251513-A2 | Acid modified adhesive compositions | ILLINOIS TOOL WORKS INC. (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4714730-A | BONDING PLASTICS | ILLINOIS TOOL WORKS INC. (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0246329-A1 | SAFETY-GLASS INTERLAYER | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4515918-A | LOW HEAT DISTORTION | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| US-4254011-A | CONTAINING A TWO-PHASE CROSSLINKED POLYACRYLATE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-03 | — | — | US | disclosed |