Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630171 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1F10ENPP1F2 | |
| SCHEMBL8633059 | 0.89 | PTGS2 (0.55) | PTGS2PTGS1F10F2TRPV1 | |
| SCHEMBL8629933 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1F10ENPP1F2 | |
| SCHEMBL8635534 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1F10ENPP1F2 | |
| SCHEMBL8629984 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1F10ENPP1F2 | |
| SCHEMBL8631441 | 0.87 | F10 (0.49) | PTGS2PTGS1F10F2 | |
| SCHEMBL7772978 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8629107 | 0.86 | PTGS2 (0.43) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8632217 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8632644 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |