Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632205 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1F10CA2CA12 | |
| SCHEMBL8628841 | 0.88 | PTGS2 (0.43) | PTGS2PTGS1F10F2 | |
| SCHEMBL8630202 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1F10CA2CA12 | |
| SCHEMBL7780360 | 0.86 | PTGS2 (0.54) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8632378 | 0.86 | PTGS2 (0.41) | PTGS2PTGS1F10F2 | |
| SCHEMBL8630861 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1F10F2 | |
| SCHEMBL8632872 | 0.84 | PTGS2 (0.39) | PTGS2PTGS1F10ALDH1A1CA2 | |
| SCHEMBL8631579 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1F10F2 | |
| SCHEMBL8631997 | 0.84 | PTGS2 (0.39) | PTGS2PTGS1F10CA2CA1 | |
| SCHEMBL8629107 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |