Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207315 | 0.83 | — | — | |
| SCHEMBL6887416 | 0.81 | KMT2A (0.39) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL2810385 | 0.79 | SOAT1 (0.42) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL11456167 | 0.79 | SOAT1 (0.42) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL7765920 | 0.79 | SOAT1 (0.42) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL26744926 | 0.79 | APP (0.48) | SPHK2SPHK1LMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3354872 | 0.79 | TP53 (0.38) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL11477514 | 0.79 | SOAT1 (0.42) | LMNAALDH1A1TP53LOXKDM4E | |
| SCHEMBL8629747 | 0.77 | SPHK2 (0.43) | SPHK2SPHK1F2 | |
| SCHEMBL7769895 | 0.74 | ALDH1A1 (0.38) | LMNAALDH1A1TP53LOXNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |