Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 2/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629723 | 0.89 | ESRRB (0.37) | ALDH1A1MAPTKDM4EL3MBTL1CTSL | |
| SCHEMBL9736778 | 0.78 | ADRB2 (0.32) | MMEACECPA1ACE2GRN | |
| SCHEMBL9523641 | 0.72 | PPARG (0.33) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL16148756 | 0.72 | KCNH2 (0.37) | ALDH1A1MAPTMTNR1AMTNR1BCTSL | |
| SCHEMBL17511793 | 0.72 | RIPK1 (0.34) | — | |
| SCHEMBL9115858 | 0.71 | PPARG (0.32) | MMEACECPA1ACE2GRN | |
| SCHEMBL9735835 | 0.70 | ADRB2 (0.32) | MMEACECPA1ACE2GRN | |
| SCHEMBL7624795 | 0.69 | RIPK1 (0.31) | — | |
| SCHEMBL9802325 | 0.69 | ATM (0.37) | ALDH1A1MAPTPOLBL3MBTL1SLC7A5 | |
| SCHEMBL8391276 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849749-A | 6-(hydroxymethyl-ethyl)pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |