Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523641 | 0.84 | PPARG (0.33) | ADRB2ADRB1ADRB3MMEACE | |
| SCHEMBL7870039 | 0.77 | KMT2A (0.37) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL9736778 | 0.76 | ADRB2 (0.32) | ADRB2ADRB1ADRB3MMEACE | |
| SCHEMBL9432002 | 0.73 | TSHR (0.36) | TP53TSHR | |
| SCHEMBL8934757 | 0.73 | MEN1 (0.33) | TSHR | |
| SCHEMBL9115858 | 0.72 | PPARG (0.32) | MMEACECPA1ACE2GRN | |
| SCHEMBL8629910 | 0.70 | MME (0.32) | MMEACECPA1ACE2GRN | |
| SCHEMBL17511793 | 0.70 | RIPK1 (0.34) | — | |
| SCHEMBL8391276 | 0.70 | — | — | |
| SCHEMBL9677414 | 0.69 | CA1 (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093363-A | Antilipemic agents | SHIONOGI & CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |