Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633093 | 0.80 | ALDH1A1 (0.36) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8630712 | 0.80 | NAMPT (0.47) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL21962695 | 0.77 | MAPT (0.53) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8631451 | 0.76 | GAA (0.51) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8634464 | 0.76 | MAPK8 (0.35) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8709676 | 0.76 | PTK2 (0.35) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8630000 | 0.75 | RAB9A (0.38) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL8634421 | 0.74 | DAO (0.55) | KMT2AMEN1RAB9AMAPTMAPK1 | |
| SCHEMBL846619 | 0.74 | — | — | |
| SCHEMBL7222896 | 0.73 | LMNA (0.46) | KMT2AMEN1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |