Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628207 | 0.69 | POLB (0.42) | KDM4EPRNPRXFP1KMT2AGAA | |
| SCHEMBL11589953 | 0.68 | KMT2A (0.42) | KDM4EPRNPRXFP1KMT2AGAA | |
| SCHEMBL9706738 | 0.63 | ALOX15 (0.49) | KDM4EKMT2AFFAR1ALOX15NOTUM | |
| SCHEMBL29987569 | 0.63 | ALDH1A1 (0.69) | KDM4EKMT2AGAAALOX15ALDH1A1 | |
| SCHEMBL437152 | 0.63 | ALDH1A1 (0.69) | KDM4EKMT2AGAAALOX15ALDH1A1 | |
| SCHEMBL972476 | 0.62 | KDM4E (0.40) | KDM4EPRNPRXFP1KMT2AGAA | |
| SCHEMBL21450909 | 0.61 | CXCR2 (0.63) | KDM4EPRNPRXFP1KMT2AGAA | |
| SCHEMBL342319 | 0.61 | ALDH1A1 (0.49) | KDM4EPRNPRXFP1KMT2AGAA | |
| SCHEMBL5445067 | 0.61 | ALDH1A1 (0.65) | KDM4EPRNPRXFP1GAAAPEX1 | |
| SCHEMBL1286047 | 0.60 | ALOX15 (0.59) | KDM4EKMT2AGAAFFAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |