Sugi Predict

Sugi Predict / Compounds / SCHEMBL437152

SCHEMBL437152

SCHEMBL437152

O=C(O)CSc1ccccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.69
▸ KMT2A Q03164 3/20 0.63
▸ MEN1 O00255 1/20 0.63
▸ PKM P14618 1/20 0.63
▸ LMNA P02545 1/20 0.61
▸ HSD17B10 Q99714 3/20 0.59
▸ HPGD P15428 3/20 0.59
▸ RAB9A P51151 3/20 0.59
▸ NPC1 O15118 2/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ KDM4E B2RXH2 2/20 0.59
▸ ALOX15 P16050 1/20 0.59
▸ MAPT P10636 1/20 0.58
▸ POLB P06746 2/20 0.58
▸ TDP1 Q9NUW8 1/20 0.58
▸ GAA P10253 1/20 0.56
▸ TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29987569 1.00 ALDH1A1 (0.69) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL7358597 0.83 KMT2A (0.61) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL11710565 0.83 KMT2A (0.61) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL13461017 0.83 LMNA (0.64) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL5717736 0.83 KMT2A (0.61) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL433102 0.81 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL30602595 0.81 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1PKMLMNA
Hydrochloric Acid SCHEMBL27355889 0.81 KMT2A (0.59) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL13463981 0.80 LMNA (0.65) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL10402212 0.80 KMT2A (0.58) ALDH1A1KMT2AMEN1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115522237-A Additive capable of improving stability of electro-coppering solution 广东利尔化学有限公司 2022-12-27 — — CN claimed
CN-109771422-A 2-(pyridine -2- sulfenyl) medical usage of the acetic acid in Killing Mycobacterium Tuberculosis infection 中国药科大学 2019-05-21 — — CN claimed
US-4175185-A ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION MEIJI SEIKA KAISHA LTD. (JP) 1979-11-20 — — US claimed
US-11827629-B2 CDGSH iron sulfur domain 2 activators and use thereof NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2023-11-28 — — US disclosed
US-11827629-B2 CDGSH iron sulfur domain 2 activators and use thereof NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2023-11-28 — — US disclosed
US-20220411418-A1 CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2022-12-29 — — US disclosed
CN-115522237-A Additive capable of improving stability of electro-coppering solution 广东利尔化学有限公司 2022-12-27 — — CN disclosed
CN-109628915-B Stable electroless copper compositions and methods for electroless copper plating on substrates 罗门哈斯电子材料有限责任公司 2021-01-26 — — CN disclosed
US-10655227-B2 Stable electroless copper plating compositions and methods for electroless plating copper on substrates ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-05-19 — — US disclosed
US-10655227-B2 Stable electroless copper plating compositions and methods for electroless plating copper on substrates ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-05-19 — — US disclosed
EP-3467148-B1 STABLE ELECTROLESS COPPER PLATING COMPOSITIONS AND METHODS FOR ELECTROLESS PLATING COPPER ON SUBSTRATES ROHM & HAAS ELECT MAT (US) 2020-02-26 — — EP disclosed
EP-1363925-B1 MACROLIDE ANTIBIOTICS GLAXO GROUP LTD (GB) 2006-11-15 — — EP disclosed
US-20060211636-A1 Macrolide Antibiotics ALIHODZIC SULEJMAN 2006-09-21 — — US disclosed
WO-2005094817-A1 MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-10-13 — — WO disclosed
US-20050215495-A1 Macrolide antibiotics ALIHODZIC SULEJMAN 2005-09-29 — — US disclosed
JP-2001288170-A METHOD FOR PRODUCING (TRIBROMOMETHYLSULFONYL) PYRIDINE SUMITOMO SEIKA CHEM CO LTD 2001-10-16 — — JP disclosed
US-4791114-A GASTROINTESTINAL DISORDERS; ANTISECRETORY AGENTS; CYTOPROTECTIVE AGENTS 501 Laboratorios Del, Dr. Esteve (ES) 1988-12-13 — — US disclosed
US-4528286-A Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) 1985-07-09 — — US disclosed
US-4175185-A ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION MEIJI SEIKA KAISHA LTD. (JP) 1979-11-20 — — US disclosed
US-3998816-A 7-[5-N-(n-Butoxyethoxy carbonyl and 2-chloroethoxy carbonyl)-amino] cephalosporins C MEIJI SEIKA KAISHA, LTD. (JA) 1976-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215495-A1 Macrolide antibiotics IL1R1, MRPL12, RPS21 ALDH1A1 2549/4885KMT2A 2302/4885MEN1 2872/4885
US-20060211636-A1 Macrolide Antibiotics IL1R1, MRPL12, RPS21 ALDH1A1 2549/4885KMT2A 2302/4885MEN1 2872/4885
US-20220411418-A1 CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF CISD2, CISD1, FECH ALDH1A1 3533/4885KMT2A 3256/4885MEN1 4247/4885
US-11827629-B2 CDGSH iron sulfur domain 2 activators and use thereof CISD2, CISD1, FECH ALDH1A1 3533/4885KMT2A 3256/4885MEN1 4247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.