SCHEMBL8630217

SCHEMBL8630217

Cc1cccc(Oc2ccc(C#N)c(C#N)c2)c1Oc1ccc(C#N)c(C#N)c1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.58
CYP19A1 P11511 1/20 0.46
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522176 0.91 AR (0.68) ARCYP19A1
SCHEMBL15268658 0.86 AR (0.75) ARCYP19A1POLBGAA
SCHEMBL23795062 0.84 AR (0.55) ARCYP19A1
SCHEMBL9747084 0.83 ALDH1A1 (0.51) ARCYP19A1POLBGAA
SCHEMBL9746262 0.83 ALDH1A1 (0.51) ARCYP19A1POLBGAA
SCHEMBL28984282 0.82 AR (0.59) ARCYP19A1POLBGAA
SCHEMBL8632256 0.82 AR (0.61) ARCYP19A1
SCHEMBL20510909 0.81 AR (0.70) ARCYP19A1POLBGAA
SCHEMBL1656112 0.81 AR (0.54) ARCYP19A1
SCHEMBL1940627 0.80 AR (0.57) ARCYP19A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed