Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 2/20 | 0.33 | |
| ▸ | CDC25A | P30304 | 10/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632477 | 0.88 | PDCD1 (0.35) | HDAC3HDAC1HDAC7HDAC2HDAC6 | |
| SCHEMBL7392958 | 0.87 | CDC25A (0.39) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7390456 | 0.84 | PDF (0.39) | PDFHDAC6ALDH1A1LMNAMEN1 | |
| SCHEMBL8630691 | 0.78 | PDCD1 (0.35) | PDCD1CD274LMNAMEN1HPGD | |
| SCHEMBL8631945 | 0.77 | PDF (0.34) | PDFCDC25ACES1HDAC3HDAC1 | |
| SCHEMBL7398238 | 0.75 | GAA (0.34) | LMNAMEN1TSHRRECQLKMT2A | |
| SCHEMBL7386864 | 0.74 | TLR8 (0.33) | PDFCDC25AALDH1A1MEN1KMT2A | |
| SCHEMBL8630245 | 0.73 | PDF (0.33) | PDFCDC25ACES1MEN1KMT2A | |
| SCHEMBL8627860 | 0.72 | MEN1 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7431775 | 0.69 | MAOA (0.41) | ALDH1A1LMNAMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |