Pyrrole

Pyrrole

SCHEMBL8630353

O=C(O)CCn1cccc1.c1cc[nH]c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.47
HPGD P15428 3/20 0.43
TSHR P16473 2/20 0.43
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
LMNA P02545 1/20 0.38
FABP3 P05413 1/20 0.37
FABP4 P15090 1/20 0.37
FABP5 Q01469 1/20 0.37
TP53 P04637 1/20 0.37
APEX1 P27695 2/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524907 0.91 EGLN3 (0.54) EGLN3HPGDTSHRMEN1KMT2A
SCHEMBL1278389 0.77 TBXAS1 (0.48) EGLN3HPGDTSHRMEN1KMT2A
Succinic Acid SCHEMBL28137806 0.76 LMNA (0.53) TSHRLMNAALDH1A1
SCHEMBL5512391 0.76 TBXAS1 (0.56) TSHRLMNAFABP4FABP5
SCHEMBL608651 0.74 TBXAS1 (0.59) TSHRLMNAFABP4FABP5MAPT
SCHEMBL2287581 0.74 TBXAS1 (0.59) TSHRLMNAFABP4FABP5MAPT
SCHEMBL5829664 0.74 TBXAS1 (0.59) TSHRLMNAFABP4FABP5MAPT
SCHEMBL31016264 0.74 TBXAS1 (0.59) TSHRLMNAFABP4FABP5MAPT
SCHEMBL1960855 0.72 TBXAS1 (0.58) TSHRLMNAFABP4FABP5MAPT
Pyrrole SCHEMBL10398511 0.70 FBP1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101787125-B Preparation method of pyrrole/N-(2-carboxyethyl) pyrrole composite nanoparticles and application thereof UNIV SHAANXI NORMAL 2012-05-23 CN disclosed
CN-101787125-B Preparation method of pyrrole/N-(2-carboxyethyl) pyrrole composite nanoparticles and application thereof UNIV SHAANXI NORMAL 2012-05-23 CN disclosed
CN-101787125-A Preparation method of pyrrole/N-(2-carboxyethyl) pyrrole composite nanoparticles and application thereof UNIV SHAANXI NORMAL 2010-07-28 CN disclosed
CN-101787125-A Preparation method of pyrrole/N-(2-carboxyethyl) pyrrole composite nanoparticles and application thereof UNIV SHAANXI NORMAL 2010-07-28 CN disclosed
US-5766934-A Chemical and biological sensors having electroactive polymer thin films attached to microfabricated devices and possessing immobilized indicator moieties ALLAGE ASSOCIATES, INC. 1998-06-16 US disclosed