SCHEMBL8630491

SCHEMBL8630491

CC(=O)OCCNc1nc(S)nc(S)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 3/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HTT P42858 2/20 0.35
ALDH1A1 P00352 6/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14544718 0.84 L3MBTL1 (0.51) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL9862275 0.79 L3MBTL1 (0.46) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL8630497 0.71 KDM4E (0.37) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL8729042 0.69 KDM4E (0.41) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL14562388 0.66 ALDH1A1 (0.50) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL68618 0.66 ALDH1A1 (0.50) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL21096269 0.66 PRMT1 (0.44) L3MBTL1KDM4EKMT2AMEN1CYP1A2
SCHEMBL28022609 0.64 L3MBTL1 (0.41) L3MBTL1KMT2AMEN1CYP1A2ALDH1A1
SCHEMBL5950512 0.64 KDM4E (0.52) L3MBTL1KDM4ERECQLKMT2AMEN1
SCHEMBL6751563 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0508390-B1 Light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1998-07-01 EP disclosed
US-5258280-A 2-amino-4,6-dimercapto-1,3,5-triazine derivatives; blackness, high covering power KONICA CORPORATION (JP) 1993-11-02 US disclosed
EP-0508390-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-10-14 EP disclosed