Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862275 | 0.76 | L3MBTL1 (0.46) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL4775385 | 0.72 | POLB (0.41) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL8630497 | 0.71 | KDM4E (0.37) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL14544718 | 0.70 | L3MBTL1 (0.51) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL8630491 | 0.69 | L3MBTL1 (0.46) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL21600848 | 0.68 | TP53 (0.42) | KDM4ERECQLL3MBTL1KMT2ACYP1A2 | |
| SCHEMBL12884491 | 0.66 | — | — | |
| SCHEMBL14562388 | 0.66 | ALDH1A1 (0.50) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL68618 | 0.66 | ALDH1A1 (0.50) | KDM4ERECQLL3MBTL1MEN1KMT2A | |
| SCHEMBL5950512 | 0.64 | KDM4E (0.52) | KDM4ERECQLL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |