Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 2/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098014 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAKDM4EL3MBTL1SLC6A2 | |
| SCHEMBL13733688 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAKDM4EL3MBTL1SLC6A2 | |
| SCHEMBL8865472 | 0.81 | PLA2G7 (0.33) | KAT7KAT6A | |
| SCHEMBL30556753 | 0.74 | SLC6A2 (0.36) | KDM4EL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23610057 | 0.69 | SLC6A2 (0.63) | SMN1; SMN2LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL31143646 | 0.69 | SLC6A2 (0.63) | SMN1; SMN2LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL477369 | 0.69 | SLC6A2 (0.63) | SMN1; SMN2LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL31143614 | 0.69 | SLC6A2 (0.63) | SMN1; SMN2LMNAKDM4EALDH1A1SLC6A2 | |
| SCHEMBL30437840 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKDM4EL3MBTL1ALDH1A1 | |
| Diphenylmethanol SCHEMBL6434457 | 0.68 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAKDM4EL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047169-C | (1-phenyl-1-heterocyclyl) methanol and (1-phenyl-1-heterocyclyl) methylamine derivatives | ASTRA AB (SE) | 1999-12-08 | — | — | CN | claimed |
| US-5712299-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | ASTRA AKTIEBOLAG (SE) | 1998-01-27 | — | — | US | claimed |
| CN-1126991-A | Novel (1-phenyl-1-heterocyclyl) methanol and (1-phenyl-1-heterocyclyl) methylamine derivatives | ASTRA AB (SE) | 1996-07-17 | — | — | CN | claimed |
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | claimed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | claimed |
| CN-1047169-C | (1-phenyl-1-heterocyclyl) methanol and (1-phenyl-1-heterocyclyl) methylamine derivatives | ASTRA AB (SE) | 1999-12-08 | — | — | CN | disclosed |
| US-5712299-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | ASTRA AKTIEBOLAG (SE) | 1998-01-27 | — | — | US | disclosed |
| CN-1126991-A | Novel (1-phenyl-1-heterocyclyl) methanol and (1-phenyl-1-heterocyclyl) methylamine derivatives | ASTRA AB (SE) | 1996-07-17 | — | — | CN | disclosed |
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |