Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.35 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733688 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL8630495 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRLMNAL3MBTL1SLC6A2 | |
| SCHEMBL1242879 | 0.76 | SMN1; SMN2 (0.87) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL8865472 | 0.74 | PLA2G7 (0.33) | — | |
| SCHEMBL8438887 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL477393 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL477633 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL30476558 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL30476552 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GAACYP17A1TSHRLMNA | |
| SCHEMBL28001042 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2GAACYP17A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496197-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2024-08-16 | — | — | CN | disclosed |