Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565235 | 0.92 | EGLN1 (0.43) | EGLN1EGLN3TET3BBOX1VEGFA | |
| SCHEMBL6565252 | 0.85 | EGLN1 (0.41) | EGLN1EGLN3TET3BBOX1VEGFA | |
| SCHEMBL6565698 | 0.83 | EGLN1 (0.40) | EGLN1EGLN3TET3BBOX1VEGFA | |
| SCHEMBL8631191 | 0.76 | CNR2 (0.38) | CNR2KDM5B | |
| SCHEMBL8779216 | 0.74 | EGLN1 (0.49) | EGLN1EGLN3VEGFAFLT1FTO | |
| Hydrochloric Acid SCHEMBL6565656 | 0.74 | EGLN1 (0.48) | EGLN1EGLN3VEGFAFLT1FTO | |
| SCHEMBL8629414 | 0.73 | KMT2A (0.46) | — | |
| SCHEMBL8627737 | 0.69 | EGLN1 (0.45) | EGLN1 | |
| SCHEMBL6567188 | 0.67 | EGLN1 (0.47) | EGLN1EGLN3VEGFAFLT1FTO | |
| SCHEMBL705432 | 0.67 | EGLN1 (0.56) | EGLN1EGLN3TET3BBOX1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726305-A | Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-10 | — | — | US | disclosed |
| US-5719164-A | Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |