Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939051 | 0.81 | GAA (0.44) | ALDH1A1CA2CA1CA9CA4 | |
| SCHEMBL284483 | 0.81 | CA2 (0.38) | GBA1ALDH1A1CA2CA1LMNA | |
| Leucine SCHEMBL29575582 | 0.71 | SLC7A5 (0.55) | LARS1GBA1ALDH1A1CA2CA1 | |
| Leucine SCHEMBL9592701 | 0.71 | SLC7A5 (0.55) | LARS1GBA1ALDH1A1CA2CA1 | |
| Leucine SCHEMBL16464665 | 0.71 | SLC7A5 (0.55) | LARS1GBA1ALDH1A1CA2CA1 | |
| Leucine SCHEMBL30462445 | 0.71 | SLC7A5 (0.55) | LARS1GBA1ALDH1A1CA2CA1 | |
| SCHEMBL31643303 | 0.71 | ALDH1A1 (0.44) | GBA1ALDH1A1CA2CA1CA9 | |
| SCHEMBL16464668 | 0.70 | ALDH1A1 (0.47) | LARS1GBA1ALDH1A1CA2CA1 | |
| SCHEMBL9592709 | 0.70 | ALDH1A1 (0.47) | LARS1GBA1ALDH1A1CA2CA1 | |
| SCHEMBL4970513 | 0.70 | LARS1 (0.40) | LARS1GBA1ALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708148-A | MUTANTS OF ESCHERICHIA COLI CELLS, DENATURING POLYPEPTIDES, REFOLDING AND INCUBATION | CIBA GEIGY CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0434605-B1 | Novel process for the production of unfused protein in E. coli | CIBA GEIGY AG (CH) | 1996-09-11 | — | — | EP | disclosed |
| US-5210028-A | Genetic engineering, production of insulin-like growth factor II in Escherichia host cell | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0434605-A2 | Novel process for the production of unfused protein in E. coli | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |