Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629514 | 0.92 | AVPR2 (0.44) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL8630141 | 0.86 | AVPR2 (0.42) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL8631919 | 0.84 | NPY2R (0.39) | AVPR1AAVPR2KMT2A | |
| SCHEMBL8630623 | 0.83 | KMT2A (0.40) | KMT2A | |
| SCHEMBL8627338 | 0.82 | AVPR2 (0.47) | AVPR1AAVPR2ABCB11HTR1ACHRM1 | |
| SCHEMBL8635138 | 0.82 | AVPR2 (0.43) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL8632071 | 0.82 | AVPR2 (0.46) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL8634479 | 0.81 | AVPR2 (0.46) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL8630121 | 0.80 | NPY2R (0.38) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL4685964 | 0.80 | AVPR2 (0.47) | AVPR1AAVPR2AVPR1BABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |