Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 17/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634051 | 0.85 | AVPR2 (0.42) | AVPR2POLB | |
| SCHEMBL4686375 | 0.85 | AVPR2 (0.56) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8634460 | 0.83 | MAPT (0.36) | POLBALDH1A1 | |
| SCHEMBL8629473 | 0.80 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL8627674 | 0.78 | AVPR2 (0.38) | AVPR2CYP2C9ALDH1A1 | |
| SCHEMBL8631906 | 0.76 | RORC (0.44) | AVPR2AVPR1APOLBALDH1A1 | |
| SCHEMBL8632674 | 0.75 | AVPR2 (0.51) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4685278 | 0.74 | AVPR2 (0.47) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL7350725 | 0.73 | AVPR2 (0.55) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8634049 | 0.73 | AVPR2 (0.42) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |