Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27390752 | 0.93 | CYP1A2 (0.50) | CYP1A2LMNATDP1HRH3SMN1; SMN2 | |
| SCHEMBL8633579 | 0.85 | CYP1A2 (0.51) | CYP1A2LMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8629603 | 0.84 | FDPS (0.51) | CYP1A2LMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27590158 | 0.81 | CYP1A2 (0.53) | CYP1A2LMNATDP1HRH3SMN1; SMN2 | |
| SCHEMBL27461429 | 0.81 | CYP1A2 (0.55) | CYP1A2LMNATDP1HRH3SMN1; SMN2 | |
| SCHEMBL7886018 | 0.76 | CYP1A2 (0.50) | CYP1A2LMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2769178 | 0.74 | SMN1; SMN2 (0.52) | CYP1A2LMNATDP1HRH3SMN1; SMN2 | |
| SCHEMBL7785095 | 0.74 | FDPS (0.46) | CYP1A2LMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27318826 | 0.73 | CYP1A2 (0.42) | CYP1A2LMNATDP1HRH3SMN1; SMN2 | |
| SCHEMBL8503990 | 0.73 | CYP1A2 (0.70) | CYP1A2LMNATDP1HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |