Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630652 | 0.85 | CYP1A2 (0.54) | CYP1A2LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL21025180 | 0.81 | CYP1A2 (0.53) | CYP1A2LMNAKDM4EALDH1A1HIF1A | |
| SCHEMBL27390752 | 0.79 | CYP1A2 (0.50) | CYP1A2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL27461429 | 0.79 | CYP1A2 (0.55) | CYP1A2LMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8629786 | 0.78 | KDM4E (0.45) | CYP1A2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL5140898 | 0.78 | CYP1A2 (0.48) | CYP1A2LMNAKDM4EALDH1A1TRPM8 | |
| SCHEMBL5862781 | 0.78 | ALDH1A1 (0.47) | CYP1A2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL4341122 | 0.76 | LMNA (0.57) | CYP1A2LMNAKDM4EALDH1A1HIF1A | |
| SCHEMBL7810409 | 0.75 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL8783322 | 0.75 | NAMPT (0.45) | CYP1A2LMNAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |