Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 7/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394363 | 0.92 | DGAT1 (0.38) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL8632724 | 0.83 | DGAT1 (0.39) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL8633239 | 0.82 | CYP2D6 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27410703 | 0.80 | DGAT1 (0.39) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL8633676 | 0.79 | EPHX2 (0.37) | DGAT1HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL26109316 | 0.77 | CYP2D6 (0.46) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL544794 | 0.77 | CYP2D6 (0.46) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL8633728 | 0.76 | DGAT1 (0.36) | DGAT1CYP2D6 | |
| SCHEMBL2331892 | 0.73 | CYP2D6 (0.44) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL31301962 | 0.73 | CYP2D6 (0.44) | DGAT1CYP2D6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |