Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632724 | 0.88 | DGAT1 (0.39) | DGAT1HDAC8MEN1KMT2AGAA | |
| SCHEMBL8632463 | 0.86 | CYP1A2 (0.35) | EPHX2LMNAUSP2HDAC8TSHR | |
| SCHEMBL8633728 | 0.81 | DGAT1 (0.36) | DGAT1MEN1KMT2AGAA | |
| SCHEMBL8630685 | 0.79 | DGAT1 (0.41) | DGAT1HDAC8HDAC1HDAC2HDAC6 | |
| SCHEMBL2331646 | 0.78 | EPHX2 (0.40) | EPHX2LMNAL3MBTL1HDAC8MEN1 | |
| SCHEMBL2336876 | 0.78 | EPHX2 (0.40) | EPHX2LMNAL3MBTL1HDAC8MEN1 | |
| SCHEMBL2332922 | 0.78 | EPHX2 (0.40) | EPHX2LMNAL3MBTL1HDAC8MEN1 | |
| SCHEMBL18306201 | 0.78 | EPHX2 (0.39) | EPHX2LMNAUSP2L3MBTL1HDAC8 | |
| SCHEMBL27686173 | 0.78 | EPHX2 (0.39) | EPHX2LMNAUSP2L3MBTL1HDAC8 | |
| SCHEMBL4230480 | 0.77 | EPHX2 (0.40) | EPHX2LMNAL3MBTL1HDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |