Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | CTSS | P25774 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632724 | 0.92 | DGAT1 (0.39) | DGAT1SLC1A1MEN1GAAKMT2A | |
| SCHEMBL8784761 | 0.89 | CTSK (0.33) | SLC1A1CTSKCTSSMEN1GAA | |
| Lithium SCHEMBL8633787 | 0.88 | CTSK (0.33) | SLC1A1CTSKCTSSMEN1GAA | |
| SCHEMBL27394363 | 0.85 | DGAT1 (0.38) | DGAT1CTSKCTSSMEN1GAA | |
| SCHEMBL8633676 | 0.81 | EPHX2 (0.37) | DGAT1MEN1GAAKMT2A | |
| SCHEMBL8633153 | 0.78 | CYP1A2 (0.33) | CTSKMEN1KMT2A | |
| SCHEMBL8630685 | 0.76 | DGAT1 (0.41) | DGAT1CYP2D6 | |
| SCHEMBL19756830 | 0.76 | CYP2D6 (0.37) | SLC1A1CTSKMEN1GAAKMT2A | |
| SCHEMBL18326687 | 0.76 | CYP2D6 (0.37) | SLC1A1CTSKMEN1GAAKMT2A | |
| SCHEMBL17548574 | 0.76 | CYP2D6 (0.37) | SLC1A1CTSKMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |