SCHEMBL467809

SCHEMBL467809

CC(=O)NC(=O)CCC(N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GSR P00390 1/20 0.54
CYP1A2 P05177 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54
GRIK3 Q13003 1/20 0.54
GRIN2B Q13224 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909135 1.00 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL8160588 0.98 GRM8 (0.52) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL31562940 0.87 GSR (0.62) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL28229088 0.83 GSR (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL6445994 0.83 KMT2A (0.53) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27760617 0.82 GRM8 (0.52) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL8176286 0.82 GRM8 (0.47) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL7049981 0.82 ALOX15 (0.59) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27890690 0.82 ALOX15 (0.59) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3678707 0.80 GSR (0.54) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20250354185-A1 BLUE PIGMENT AND BIOSYNTHESIS METHOD THEREOF VERTEXYN BIOWORKS CO LTD (CN) 2025-11-20 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
WO-2025068210-A2 USE OF A MARKER SET FOR DETERMINING THE AGGRESSIVENESS OF A PROSTATE TUMOR NUMARES AG (DE) 2025-04-03 WO claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
WO-2025068209-A1 USE OF A MARKER SET FOR DETERMINING THE RISK OF DEVELOPING CASTRATION-RESISTANT PROSTATE CANCER NUMARES AG (DE) 2025-04-03 WO claimed
CN-119385996-A Application of N-acetylglutamine in product for preventing or treating ulcerative colitis and product 南方医科大学深圳医院 2025-02-07 CN claimed
CN-118360308-B Construction method and application of metabolic engineering bacteria for biosynthesis of N-acetyl cerulosa by using glutamic acid as substrate 南京合谷生命生物科技有限公司 2024-09-27 CN claimed
CN-118184576-B Natural blue pigment and biosynthesis method thereof 南京合谷生命生物科技有限公司 2024-08-16 CN claimed
CN-118360308-A Construction method and application of metabolic engineering bacteria for biosynthesis of N-acetyl cerulosa by using glutamic acid as substrate 南京合谷生命生物科技有限公司 2024-07-19 CN claimed
EP-2024423-B1 AMINO-ACID FUNCTIONAL SILOXANES, METHODS OF PREPARATION AND APPLICATIONS DOW CORNING (US) 2009-12-09 EP claimed
WO-2006086731-A2 METHOD FOR IDENTIFYING THE RISK OF PRETERM DELIVERY THE GOV'T.T OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2006-08-17 WO claimed
US-20060029563-A1 Cutanceous metabolic bio-activator JEAN-NOEL THOREL (FR) 2006-02-09 US claimed
US-6770758-B2 USING CONJUGATING LIGAND TO A THERMO-SENSITIVE POLYMERS AND LIGAND SPECIFICALLY RECOGNIZES A POLYSACCHARIDE, AND THE THERMO-SENSITIVE POLYMER FEATURES A LOWER CRITICAL SOLUTION TEMPERATURE (LCST) INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2004-08-03 US claimed
US-20040127701-A1 POLYSACCHARIDE SEPARATION METHOD INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2004-07-01 US claimed
EP-0815833-B1 Malodour preventing agents GIVAUDAN SA (CH) 2003-04-09 EP claimed
EP-0627410-B1 N-ACYLGLUTAMINE DERIVATIVE KYOWA HAKKO KOGYO KK (JP) 1997-10-29 EP claimed
EP-0440058-B1 Cosmetic composition KYOWA HAKKO KOGYO KK (JP) 1994-10-12 EP claimed
US-5112613-A Enhanced moisture retention, skin care KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-05-12 US claimed
EP-0440058-A1 Cosmetic composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127701-A1 POLYSACCHARIDE SEPARATION METHOD ALG1, CSGALNACT1, STT3B GRM8 2099/4885GRM6 1163/4885GRIN2D 3838/4885
US-20250354185-A1 BLUE PIGMENT AND BIOSYNTHESIS METHOD THEREOF ASNS, GLUL, GALE GRM8 1761/4885GRM6 1828/4885GRIN2D 724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.