SCHEMBL2909135

SCHEMBL2909135

CC(=O)NC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GSR P00390 1/20 0.54
CYP1A2 P05177 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54
GRIK3 Q13003 1/20 0.54
GRIN2B Q13224 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467809 1.00 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL8160588 0.98 GRM8 (0.52) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL31562940 0.87 GSR (0.62) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL28229088 0.83 GSR (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL6445994 0.83 KMT2A (0.53) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27760617 0.82 GRM8 (0.52) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL8176286 0.82 GRM8 (0.47) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL7049981 0.82 ALOX15 (0.59) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27890690 0.82 ALOX15 (0.59) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3678707 0.80 GSR (0.54) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1714650-B1 Arginine-containing compositions for increasing blood flow AJINOMOTO KK (JP) 2010-08-18 EP claimed
EP-0547099-B1 PRODUCT CONTAINING GROWTH FACTOR AND GLUTAMINE AND USE OF GROWTH FACTOR FOR THE TREATMENT OF INTESTINAL MUCOSA PHARMACIA & UPJOHN AB (SE) 1997-07-30 EP claimed
EP-0263291-A2 Process for the fermentative production of L-arginine Degussa Aktiengesellschaft (DE) 1988-04-13 EP claimed
CN-113979886-B Protective amino acid with side chain being amide and preparation method thereof 成都市科隆化学品有限公司 2024-05-24 CN disclosed
EP-2225386-A2 PROCESS FOR THE ENZYMATIC PREPARATION OF A GAMMA-GLUTAMYL COMPOUND Unilever PLC (GB) 2010-09-08 EP disclosed
WO-2009083454-A2 PROCESS FOR THE ENZYMATIC PREPARATION OF A GAMMA-GLUTAMYL COMPOUND UNILEVER PLC (GB) 2009-07-09 WO disclosed
US-20090169704-A1 Process for the enzymatic preparation of a gamma-glutamyl compound CONOPCO, INC. D/B/A UNILEVER 2009-07-02 US disclosed
EP-1639991-A2 Skin and tissue care and/or treatment composition Mandorlo Investment GmbH (LU) 2006-03-29 EP disclosed
EP-1096918-B1 SKIN AND TISSUE CARE AND/OR TREATMENT AGENT MANDORLO INVEST GMBH (LU) 2005-11-09 EP disclosed
US-6448256-B1 PRECURSORS OF N-SUBSTITUTED DERIVATIVES OF 6-AMINOURACILS, 6-AMINOISOCYTOSINES, GUANINES AND 2-AMINOADENINES HAVING A CLEAVABLE ESTER GROUP; GREATER WATER SOLUBILITY AND ORAL BIOAVAILABILITY; TREATING GRAM POSITIVE BACTERIAL INFECTIONS UNIVERSITY OF MASSACHUSETTS 2002-09-10 US disclosed
EP-1185517-A1 ANTIBIOTIC PRODRUGS University of Massachusetts (US) 2002-03-13 EP disclosed
EP-1096918-A2 SKIN AND TISSUE CARE AND/OR TREATMENT AGENT Mandorlo Investment GmbH (LU) 2001-05-09 EP disclosed
WO-2000071523-A1 ANTIBIOTIC PRODRUGS UNIVERSITY OF MASSACHUSETTS (US) 2000-11-30 WO disclosed
WO-2000003689-A2 SKIN AND TISSUE CARE AND/OR TREATMENT AGENT MANDORLO INVESTMENT GMBH (LU) 2000-01-27 WO disclosed
EP-0466030-B1 N-acyl dipeptides and their use DEGUSSA (DE) 1995-10-11 EP disclosed
EP-0466030-A2 N-acyl dipeptides and their use DEGUSSA AG (DE) 1992-01-15 EP disclosed
EP-0263291-A2 Process for the fermentative production of L-arginine Degussa Aktiengesellschaft (DE) 1988-04-13 EP disclosed