Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327005 | 0.88 | SHBG (0.43) | PTGS1PTGS2ESR1ESR2PTPN1 | |
| SCHEMBL8377055 | 0.85 | CA1 (0.48) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL10460178 | 0.84 | SHBG (0.41) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL23750682 | 0.82 | PTPN1 (0.47) | ESR1PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL862843 | 0.81 | PTGS2 (0.43) | PTGS2ESR1PTPN1L3MBTL1KDM4E | |
| SCHEMBL27993024 | 0.79 | SHBG (0.42) | PTGS1PTGS2ESR1ESR2PTPN1 | |
| SCHEMBL28401208 | 0.77 | ALOX5 (0.45) | PTGS2CA1CA2ALOX5GAA | |
| SCHEMBL27639291 | 0.77 | CYP3A4 (0.53) | PTPN1MEN1GAAG6PDKMT2A | |
| SCHEMBL18092271 | 0.76 | SKP2 (0.35) | ESR1ESR2L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL23712434 | 0.76 | CYP4F2 (0.39) | PTGS1ESR1ESR2PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |
| US-4754077-A | HINDERED PHENOLS, METHANOL, FORMALDEHYDE, PHENOL COMPOUND, MANNICH BASE CATALYST | ETHYL CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0116712-B1 | SYNTHESIS OF HINDERED PHENOLS | ETHYL CORPORATION (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0116712-A1 | Synthesis of hindered phenols | ETHYL CORPORATION (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984002336-A1 | ANTIOXIDANT SYNTHESIS | ETHYL CORP (US) | 1984-06-21 | — | — | WO | disclosed |