Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453874 | 1.00 | NAAA (0.50) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL11589171 | 1.00 | NAAA (0.50) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL11590190 | 1.00 | NAAA (0.50) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL450994 | 0.98 | NAAA (0.49) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL8378630 | 0.94 | NAAA (0.44) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL8693535 | 0.90 | PPM1B (0.40) | NAAAEPHX1HTTALDH1A1PPM1B | |
| SCHEMBL451499 | 0.89 | NAAA (0.56) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL8630971 | 0.89 | NAAA (0.56) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL4350675 | 0.87 | NAAA (0.58) | NAAAEPHX1HTTALDH1A1L3MBTL1 | |
| SCHEMBL11590153 | 0.87 | NAAA (0.58) | NAAAEPHX1HTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| US-5760025-A | ADMINISTERING TESTOSTERONE 5A-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5717088-A | REACTING WITH A CYANOPHOSPHATE IN THE PRESENCE OF AN ALKALI METAL CYANIDE | SANKYO COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5698720-A | INTERMEDIATES FOR TESTOSTERONE 5-ALPHA-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0567271-B1 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO CO (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0725074-A2 | Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives | SANKYO COMPANY LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5536714-A | Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-16 | — | — | US | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |
| EP-0567271-A2 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |