Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378630 | 0.92 | NAAA (0.44) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL450994 | 0.92 | NAAA (0.49) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL11590190 | 0.90 | NAAA (0.50) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL11589171 | 0.90 | NAAA (0.50) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL8631017 | 0.90 | NAAA (0.50) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL453874 | 0.90 | NAAA (0.50) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL8691325 | 0.88 | ALDH1A1 (0.48) | NAAAALDH1A1EPHX1HCAR2LMNA | |
| SCHEMBL6442932 | 0.86 | NAAA (0.47) | NAAAALDH1A1EPHX1HCAR2AKT1 | |
| SCHEMBL10955183 | 0.85 | NAAA (0.39) | PPM1BPTPN1PPP1CCNAAAALDH1A1 | |
| SCHEMBL6443077 | 0.84 | NAAA (0.50) | NAAAALDH1A1EPHX1HCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |