Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450994 | 0.96 | NAAA (0.49) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL11590190 | 0.94 | NAAA (0.50) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL453874 | 0.94 | NAAA (0.50) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL11589171 | 0.94 | NAAA (0.50) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL8631017 | 0.94 | NAAA (0.50) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL8693535 | 0.92 | PPM1B (0.40) | NAAAEPHX1HTTPPM1BPTPN1 | |
| SCHEMBL8691011 | 0.89 | NAAA (0.50) | NAAAEPHX1HTTHCAR2ALDH1A1 | |
| SCHEMBL450933 | 0.85 | NAAA (0.54) | NAAAEPHX1HTTHCAR2ALDH1A1 | |
| SCHEMBL8375449 | 0.83 | ALDH1A1 (0.50) | NAAAEPHX1HTTALDH1A1CYP2C19 | |
| SCHEMBL8630971 | 0.83 | NAAA (0.56) | NAAAEPHX1HTTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922888-A | Process for removal of diol as impurity in cyclic carbonic acid ester | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0735034-B1 | Process for removal of diol as impurity in cyclic carbonic acid ester | MITSUI CHEMICALS INC (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0735034-A1 | Process for removal of diol as impurity in cyclic carbonic acid ester | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |