Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383872 | 0.86 | ALDH1A1 (0.62) | RAB9ANPC1L3MBTL1CA1CA2 | |
| SCHEMBL12418676 | 0.84 | PLK1 (0.49) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL863035 | 0.83 | KMT2A (0.49) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL12410190 | 0.83 | KMT2A (0.64) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL1706751 | 0.82 | CA1 (0.67) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7623974 | 0.80 | KMT2A (0.69) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL11752289 | 0.80 | KMT2A (0.74) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL20477190 | 0.80 | HPGD (0.68) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL3025651 | 0.80 | SMN1; SMN2 (0.55) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7621996 | 0.80 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |
| US-20100081782-A1 | ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME | EKWURIBE NNOCHIRI N | 2010-04-01 | — | — | US | disclosed |
| US-7335751-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2008-02-26 | — | — | US | disclosed |