Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863105 | 0.83 | RAB9A (0.58) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18085803 | 0.81 | NPC1 (0.51) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18098058 | 0.75 | MEN1 (0.58) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL19909722 | 0.75 | SMN1; SMN2 (0.44) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18573170 | 0.74 | POLB (0.53) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL10425771 | 0.74 | GAA (0.43) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL10425627 | 0.74 | HPGD (0.54) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL13383872 | 0.74 | ALDH1A1 (0.62) | GAANPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL15564138 | 0.74 | L3MBTL1 (0.44) | KMT2AMEN1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18085799 | 0.72 | MMP13 (0.56) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |
| US-20100081782-A1 | ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME | EKWURIBE NNOCHIRI N | 2010-04-01 | — | — | US | disclosed |
| US-7335751-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2008-02-26 | — | — | US | disclosed |