⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428511 | 0.80 | SLC1A3 (0.32) | — | |
| SCHEMBL27812618 | 0.80 | SLC1A3 (0.32) | — | |
| SCHEMBL8431959 | 0.80 | FAAH (0.30) | — | |
| SCHEMBL9695572 | 0.77 | ATM (0.44) | — | |
| SCHEMBL2386153 | 0.73 | — | — | |
| SCHEMBL2386156 | 0.73 | — | — | |
| SCHEMBL9461991 | 0.73 | MEN1 (0.44) | — | |
| SCHEMBL9462196 | 0.73 | MEN1 (0.44) | — | |
| SCHEMBL19932590 | 0.73 | — | — | |
| SCHEMBL17910023 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712388-A | Method of preparing a derivative of optically active azetidin-2-one | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5286721-A | Antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| WO-1992006978-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-30 | — | — | WO | disclosed |