Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075230 | 0.74 | CHRM2 (0.47) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL9071084 | 0.74 | CHRM2 (0.47) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL82414 | 0.73 | POLB (0.59) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL13453301 | 0.73 | POLB (0.59) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL11457824 | 0.71 | MAPT (0.46) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL8809759 | 0.70 | ALOX5 (1.00) | ALOX5POLBTHRBPKM | |
| SCHEMBL8633227 | 0.69 | POLB (0.71) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL6323573 | 0.69 | ALOX5 (0.54) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL8631339 | 0.69 | POLB (0.70) | ALOX5POLBCHRM2MEN1CHRM4 | |
| SCHEMBL104309 | 0.69 | CHRM2 (0.50) | ALOX5POLBCHRM2MEN1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |