Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627619 | 0.91 | F10 (0.37) | F10PTGS2CA12CA2CA9 | |
| SCHEMBL8630033 | 0.85 | F10 (0.39) | F10PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL7777305 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8628074 | 0.82 | F10 (0.40) | F10PTGS2PTGS1F2PRSS1 | |
| SCHEMBL8629763 | 0.82 | F10 (0.39) | F10PTGS2PTGS1F2PRSS1 | |
| SCHEMBL8632806 | 0.82 | F10 (0.36) | F10PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL8632244 | 0.82 | PTGS2 (0.45) | F10PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8629352 | 0.82 | F10 (0.38) | F10PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL8631157 | 0.80 | F10 (0.36) | F10PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL8629956 | 0.80 | PTGS2 (0.37) | F10PTGS2PTGS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |