Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634446 | 0.91 | F10 (0.41) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8630033 | 0.85 | F10 (0.39) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8632687 | 0.85 | PTGS1 (0.42) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7779634 | 0.83 | PTGS2 (0.47) | PTGS1PTGS2 | |
| SCHEMBL8629795 | 0.82 | PTGS2 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8631385 | 0.82 | F10 (0.39) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8632806 | 0.82 | F10 (0.36) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8629763 | 0.82 | F10 (0.39) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8628872 | 0.82 | PTGS2 (0.47) | F10F2PTGS1PTGS2 | |
| SCHEMBL8631157 | 0.80 | F10 (0.36) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |