Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632173 | 0.91 | F10 (0.36) | F10CNR1PTGS2PTGS1CA12 | |
| SCHEMBL8629956 | 0.90 | PTGS2 (0.37) | F10HTTPTGS2PTGS1CA12 | |
| SCHEMBL8631606 | 0.89 | HTR7 (0.39) | F10CNR1HTTPTGS2PTGS1 | |
| SCHEMBL8628555 | 0.86 | KDM4E (0.38) | F10HTTPTGS2PTGS1CA12 | |
| SCHEMBL8632316 | 0.85 | PTGS1 (0.40) | F10PTGS2PTGS1CA2CA9 | |
| SCHEMBL7777922 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8629795 | 0.82 | PTGS2 (0.40) | F10PTGS2PTGS1NR1H3 | |
| SCHEMBL8635045 | 0.82 | PDE9A (0.42) | F10PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL8631385 | 0.82 | F10 (0.39) | F10PTGS2PTGS1CA12CA1 | |
| SCHEMBL8630541 | 0.81 | PTGS2 (0.57) | F10PTGS2PTGS1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |