Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631501 | 0.84 | SLC6A4 (0.44) | ALDH1A1KDM4EPOLBCYP2D6MEN1 | |
| SCHEMBL8631008 | 0.80 | RECQL (0.67) | ALDH1A1POLBKMT2AHTR1AADRA2A | |
| SCHEMBL108678 | 0.77 | KDM4E (0.70) | KDM4ECYP2D6MEN1CYP1A2CYP3A4 | |
| SCHEMBL2316901 | 0.76 | CYP2D6 (0.82) | ALDH1A1KDM4ECYP2D6MEN1CYP1A2 | |
| SCHEMBL10833328 | 0.74 | KDM4E (0.71) | ALDH1A1KDM4EPOLBCYP2D6MEN1 | |
| SCHEMBL29520874 | 0.73 | RECQL (0.53) | POLBCYP2D6CYP1A2ADRA2AHSD17B10 | |
| SCHEMBL6977835 | 0.72 | RECQL (0.51) | POLBCYP1A2ADRA2AHSD17B10TSHR | |
| SCHEMBL4750999 | 0.71 | HTR2B (0.67) | ALDH1A1KDM4EHTR1ADRD2HTR2B | |
| SCHEMBL12237371 | 0.71 | KDM4E (0.76) | ALDH1A1KDM4EPOLBCYP2D6MEN1 | |
| SCHEMBL6231529 | 0.71 | KDM4E (0.74) | ALDH1A1KDM4EPOLBCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780475-A | Antipsychotic indazole derivatives | MERCK, SHARP & DOHME LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |