Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631393 | 0.91 | KMT2A (0.42) | KMT2AGAAALDH1A1GGT1PTGDR2 | |
| SCHEMBL8631537 | 0.90 | EDNRB (0.41) | KMT2AALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL8630980 | 0.89 | KMT2A (0.39) | KMT2AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL8634609 | 0.88 | KMT2A (0.45) | KMT2AGAAALDH1A1GGT1PTGDR2 | |
| SCHEMBL8628674 | 0.88 | PTGS2 (0.44) | KMT2AMAPTPOLBMEN1NPSR1 | |
| SCHEMBL8630567 | 0.87 | EDNRB (0.41) | KMT2AALDH1A1PTGDR2MAPTPOLB | |
| SCHEMBL8629114 | 0.87 | ALDH1A1 (0.36) | KMT2AGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8629013 | 0.87 | PPARA (0.39) | MAPTCYP2C9 | |
| SCHEMBL8627950 | 0.87 | MAPT (0.38) | KMT2AALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL8631438 | 0.87 | CYP1A2 (0.46) | KMT2AGAAALDH1A1GGT1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |