Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631944 | 0.91 | KMT2A (0.44) | KMT2AGAASTAT3ALDH1A1GGT1 | |
| SCHEMBL8628839 | 0.90 | EDNRB (0.41) | KMT2AALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL8632202 | 0.89 | MAPT (0.39) | KMT2AGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8630859 | 0.88 | PTGS2 (0.44) | KMT2AMAPTPOLBMEN1NPSR1 | |
| SCHEMBL8634609 | 0.88 | KMT2A (0.45) | KMT2AGAASTAT3ALDH1A1GGT1 | |
| SCHEMBL8631576 | 0.87 | MAPT (0.41) | KMT2AGAAALDH1A1MAPTPOLB | |
| SCHEMBL8629104 | 0.87 | ALDH1A1 (0.36) | KMT2AGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8631722 | 0.87 | PPARA (0.41) | PPARA | |
| SCHEMBL8631438 | 0.87 | CYP1A2 (0.46) | KMT2AGAAALDH1A1GGT1MAPT | |
| SCHEMBL8635116 | 0.85 | PTGS2 (0.48) | KMT2AGAASTAT3ALDH1A1GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |