Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
| ▸ | CDC25A | P30304 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632480 | 0.88 | HPGD (0.34) | TP53ADRA2ASLC6A2SLC6A4DRD3 | |
| SCHEMBL7392961 | 0.85 | CDC25A (0.38) | CDC25ACES1BCHEACHEALDH1A1 | |
| SCHEMBL7390458 | 0.80 | PDF (0.39) | PDFFPR2HDAC6TP53NPC1 | |
| SCHEMBL8630694 | 0.79 | HPGD (0.35) | TP53ADRA2ASLC6A2SLC6A4DRD3 | |
| SCHEMBL8631941 | 0.77 | PDF (0.33) | PDFCDC25ACES1HDAC6HDAC3 | |
| SCHEMBL7386866 | 0.74 | PDF (0.32) | PDFCDC25ACES1 | |
| SCHEMBL7398242 | 0.73 | GAA (0.33) | CYP1A2CHRM2HTR1AADRA2ATSHR | |
| SCHEMBL7392958 | 0.70 | CDC25A (0.39) | CDC25ACES1ACHETSHRALDH1A1 | |
| SCHEMBL7391109 | 0.70 | CDC25A (0.46) | CDC25ACES1ACHEMAPTALDH1A1 | |
| SCHEMBL7392955 | 0.69 | CDC25A (0.37) | CDC25ACES1BCHEACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |