Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632480 | 0.90 | HPGD (0.34) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL7395913 | 0.81 | GAA (0.35) | MEN1KMT2ALMNAADRA2ASLC6A2 | |
| SCHEMBL8631945 | 0.79 | PDF (0.34) | NPSR1MEN1KMT2ALMNAADRA2A | |
| SCHEMBL8630691 | 0.79 | PDCD1 (0.35) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL8632477 | 0.77 | PDCD1 (0.35) | MEN1KMT2ALMNATHRBPDCD1 | |
| SCHEMBL8702342 | 0.76 | MEN1 (0.32) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL7398242 | 0.76 | GAA (0.33) | MEN1KMT2ALMNAADRA2ASLC6A2 | |
| SCHEMBL8629912 | 0.72 | MAOA (0.46) | HPGDMEN1KMT2ALMNAMAOA | |
| SCHEMBL7395911 | 0.70 | RECQL (0.36) | HPGDMEN1KMT2ALMNAADRA2A | |
| SCHEMBL7398238 | 0.68 | GAA (0.34) | MEN1KMT2ALMNAADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |