SCHEMBL863198

SCHEMBL863198

CCn1c(=O)n(C(C)O)c(=O)n(C(C)O)c1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 4/20 0.39
GSK3B P49841 4/20 0.39
SLC6A2 P23975 5/20 0.35
RGS4 P49798 1/20 0.33
RGS8 P57771 1/20 0.33
HPD P32754 2/20 0.31
POLB P06746 1/20 0.31
PLA2G4A P47712 1/20 0.31
SLC6A4 P31645 1/20 0.30
LGMN Q99538 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1244237 0.83 ALDH1A1 (0.31)
SCHEMBL19993561 0.81 GSK3B (0.47) GSK3AGSK3BSLC6A2RGS4RGS8
SCHEMBL14283656 0.76 KDM4E (0.38)
SCHEMBL26157277 0.74 PDE4A (0.34)
SCHEMBL863325 0.74 APEX1 (0.47) POLB
SCHEMBL14037107 0.73 ADORA2B (0.32)
SCHEMBL14382745 0.73 GSK3A (0.39) GSK3AGSK3BSLC6A2RGS4RGS8
SCHEMBL10167158 0.71
SCHEMBL2446004 0.71 GSK3B (0.48) GSK3AGSK3BPOLB
SCHEMBL25990302 0.70 GSK3A (0.41) GSK3AGSK3BRGS4RGS8HPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142978-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142982-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed