Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698910 | 0.90 | HRH3 (0.40) | HRH3DRD4HRH2HRH1ALDH1A1 | |
| SCHEMBL8636548 | 0.86 | GFER (0.42) | HTR2AHTR2CHRH3ALDH1A1MAPK1 | |
| SCHEMBL8632705 | 0.85 | CYP2C9 (0.42) | HRH3HRH2HRH1ALDH1A1CYP2D6 | |
| SCHEMBL8633634 | 0.82 | CYP2C9 (0.46) | HRH3HRH2HRH1ALDH1A1CYP2D6 | |
| SCHEMBL8635264 | 0.80 | CYP2C9 (0.44) | HRH3HRH2HRH1ALDH1A1CYP2D6 | |
| SCHEMBL8634057 | 0.75 | CYP2C9 (0.43) | HRH3HRH2HRH1ALDH1A1CYP2D6 | |
| SCHEMBL8635770 | 0.75 | ROCK2 (0.49) | KMT2ADRD4ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8632213 | 0.74 | SLC2A1 (0.43) | KMT2AALDH1A1TSHRHIF1AF10 | |
| Hydrochloric Acid SCHEMBL8636995 | 0.74 | CYP2C9 (0.42) | HRH3HRH2HRH1ALDH1A1CYP2D6 | |
| SCHEMBL8630430 | 0.73 | ITGB3 (0.45) | HRH3HRH2HRH1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |